Sitagliptin is utilized primarily to manage which of the following conditions?

Sitagliptin is primarily utilized to manage diabetes mellitus, specifically type 2 diabetes. It is part of a class of medications known as DPP-4 inhibitors, which work by enhancing the body's own ability to lower blood sugar levels. Sitagliptin functions by increasing the levels of incretin hormones, which play a role in regulating blood glucose. When blood sugar levels rise after eating, incretins help to stimulate the pancreas to release insulin and decrease the amount of glucagon produced by the liver, thus leading to a reduction in overall blood sugar levels.

The effectiveness of sitagliptin in controlling blood glucose makes it a key therapeutic option for those managing type 2 diabetes. It is often used in conjunction with diet and exercise to improve glycemic control. This specific role distinguishes it clearly from the other options listed, each of which pertains to different health conditions that are not addressed by sitagliptin.