What is an expected side effect of trazodone?

Trazodone is an antidepressant commonly used to treat major depressive disorder and anxiety. One of the well-known side effects of trazodone is fatigue, which can occur due to its sedative properties. The medication works by modifying the levels of neurotransmitters in the brain, including serotonin, and this alteration can cause a calming effect, making patients feel more fatigued or drowsy, particularly when they first start taking the medication or when their dosage is increased.

While other side effects associated with trazodone may include weight gain and dry skin, these are less commonly noted compared to fatigue. Insomnia, on the other hand, is typically treated by trazodone, given its sedative effects, making fatigue a more likely and expected side effect for individuals taking this medication. Understanding these effects can help healthcare providers monitor and manage the patient's response to treatment effectively.