When teaching a client about prednisone, which statement is accurate?

The statement that prednisone may cause weight gain is accurate because one of the common side effects of corticosteroids like prednisone is an increase in appetite and fluid retention, which can lead to significant weight gain over time. Prednisone can alter the body’s metabolism and fat distribution, resulting in changes in weight. Educating clients about this potential effect is crucial so they can monitor their weight and discuss any concerns with their healthcare provider.

In contrast, taking prednisone in the evening on an empty stomach is generally not recommended; it is usually advised to take it in the morning with food to minimize gastric irritation. Abruptly stopping prednisone can lead to withdrawal symptoms and may even exacerbate certain conditions, so it's important to taper off under a doctor's guidance. Lastly, while blood pressure may increase while taking this medication due to fluid retention and other factors, the more direct and prevalent side effect regarding client education often focuses on the aspect of weight gain. Thus, while there are indeed multiple considerations when teaching clients about medication, the emphasis on weight gain is particularly relevant in this context.