Which prescribed medication for an NPO client requires clarification with the healthcare provider?

The correct answer highlights the importance of understanding the implications of administering certain medications to a client who is NPO (nil per os), which means they are not allowed to take anything by mouth. Glipizide is an oral hypoglycemic agent used to manage blood sugar levels in patients with type 2 diabetes. Since this medication is typically taken orally and relies on gastrointestinal absorption, it is not appropriate to administer it to an NPO patient without an alternative route or clarification from a healthcare provider regarding an appropriate plan.

In contrast, medications like metoprolol, phenytoin, and levothyroxine may have specific formulations, such as IV options for certain situations, or there may be considerations for administration based on the clinical context that would not necessitate clarification in the same way. Understanding medication routes and the implications of a patient’s dietary restrictions is essential for safe and effective nursing care.